Meiotic abnormalities and spermatogenic parameters in severe oligoasthenozoospermia
نویسندگان
چکیده
منابع مشابه
Meiotic anomalies in infertile men with severe spermatogenic defects.
BACKGROUND This study was aimed at evaluating the rate of pairing failure in pachytene spermatocytes of patients presenting either an obstructive (O) or a non-obstructive (NO) infertility. METHODS Forty-one patients and 13 controls underwent testicular biopsy. Among the patients, 19 had an O infertility and 22 a NO infertility. Preparations of all patients and controls were Giemsa-stained, an...
متن کاملMeiotic studies in two human reciprocal translocations and their association with spermatogenic failure.
BACKGROUND Reciprocal translocations are often associated with infertility in male carriers. However, some carriers present normal semen profiles and are identified because of repetitive pregnancy failures. METHODS Here, we report two different cases of reciprocal translocations. The first patient carried a t(10;14) and was normozoospermic. The second patient carried a t(13;20) and was azoosp...
متن کاملThe whole meiotic process can occur in vitro in untransformed rat spermatogenic cells.
The aim of the present study was to assess whether the whole meiotic process of spermatogenic cells is able to take place in vitro. Fragments of seminiferous tubules from 20- to 22- or 28-day-old rats were seeded in medium containing 0.2% fetal calf serum in bicameral chambers and then cultured for 4 weeks in a chemically defined medium. The differentiation of meiotic germinal cells was followe...
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Prezado Editor, Cumprimentamos os autores do artigo publicado, sob o título “O Impacto da Obesidade Isolada na Função do Ventrículo Direito em Adultos Jovens”1. Entendemos que as alterações hemodinâmicas próprias da obesidade poderiam modificar os parâmetros ecocardiográficos alterados nesse estudo, ou seja, o aumento da volemia traria um readequamento dos parâmetros de função ventricular sem q...
متن کاملAssociation of three isoforms of the meiotic BOULE gene with spermatogenic failure in infertile men.
The complex process of spermatogenesis requires the expression and precise coordination of a multitude of genes. Abnormal function of such genes is frequently associated with male infertility. Among these candidates is the human BOULE gene that is a possible fundamental mediator of meiotic transition. In this study, we describe for the first time the existence of three BOULE transcript variants...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 1999
ISSN: 0268-1161,1460-2350
DOI: 10.1093/humrep/14.2.375